Originally produced as Call Me Jacky at The Oxford Playhouse (Oxford, UK) in 1967, starring Sybil Thorndike, the play eventually caught the attention of producer Robert Whitehead, who viewed it as an ideal star vehicle for Katharine Hepburn. Hepburn agreed to commit to a pre-Broadway tryout run of six weeks (which ultimately was expanded to twelve), a twelve-week engagement in New York City, and a subsequent six-month national tour.
The play had pre-Broadway engagements in Philadelphia, Washington, D.C., New Haven, Connecticut, Boston, and Toronto.
The play opened on Broadway on February 3, 1976, at the Broadhurst Theatre, where it ran for 79 performances. In addition to Hepburn, the cast included Christopher Reeve as Nicky and Charlotte Jones as Dubois. The director was Noel Willman.
While the play garnered mediocre reviews, critics — particularly Clive Barnes of The New York Times, who wrote a lengthy feature praising the actress for the February 15 Sunday Arts & Leisure section — were charmed by Hepburn's performance. Barnes wrote: "Miss Hepburn with her radiantly raddled beauty, her grace and meticulous theatrical sensibility—shown in the jerk of an eyebrow, the twitch of a corner of the mouth—is per fectly remarkable."
Nine weeks into the run, Hepburn asked to be released from her contract in order to film Olly Olly Oxen Free, and the production shut down. In October she started the national tour in Denver, then proceeded to Vancouver, San Francisco, and Los Angeles where, a few days after opening at Ahmanson Theatre, she fractured her ankle. After missing two performances, she returned to the play in a wheelchair. Following Los Angeles, the tour continued to Chicago's Merle Reskin Theatre, San Diego and Phoenix, where it closed in March 1977. She made national headlines when, angered by an audience member who took a flash photograph, she wheeled herself to the edge of the stage and launched into a bombastic tirade, calling the offender a "pig" and accusing her of having "no consideration for actors trying to concentrate during difficult scenes or the people who paid good money to come here.
The play's sole Tony Award nomination went to Ben Edwards for Best Scenic Design.